T lymphocyte and cancer cell, illustration

Protein Discovered That Aids Tumors to Evade Immune System

Clinical data and samples from cancer patients with 10 different types of the disease were analyzed, and the researchers observed that individuals with liver, head and neck, and stomach cancers, who have lower levels of this protein in their tumors had higher chances of survival.

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Neuron system

Researchers ID 40 Genes that Thwart Axon Regeneration in CNS Cells

When the researchers suppressed those genes in mouse models of glaucoma they were able to regenerate the damaged axons. The findings could eventually lead to developing therapies for patients of stroke, spinal cord damage, or traumatic brain injuries—avenues that don't currently exists.

FDA Approves Myriad BRACAnalysis CDx for Lynparza in Metastatic Pancreatic Cancer

According to Myriad, it is the first and only genetic test approved by the FDA as a CDx designed to help identify patients with metastatic pancreatic cancer who have a germline BRCA mutation and are candidates for treatment with Lynparza.
elderly man with head breaking apart

Feasibility Study Finds Informative Digital Biomarkers of Dementia

Combining wearable devices, handheld devices and digital apps lets researchers tell the difference between people with early dementia and those without it.

Are Biomarkers in Semen the Future of Prostate Cancer Screening?

Semen could be considered a liquid biopsy of the organs of male reproductive system—specifically, of the prostate gland. This is convenient. Semen is, potentially,...
Point mutation, illustration

Treating Ultrarare Diseases, One Patient at a Time

With the aid of the n-lorem Foundation, doctors and patients now have hope of finding treatments to the most rare of genetic diseases.

Promega to Develop MSI Technology as CDx to Merck’s Keytruda

Promega’s MSI testing is designed to functionally measure the genomic accumulation of insertion or deletion (INDEL) errors caused by a deficient mismatch-repair system (dMMR) that occurs in certain types of solid tumors.
remdesivir covid-19 liquid medication background

COVID-19 Antiviral Treatment Remdesivir’s Effectiveness Boosted 10X by Hepatitis C Drug

The study's authors suggested their work could lead to a combination antiviral therapy for COVID-19, which could be especially helpful to unvaccinated people who become infected and to vaccinated people who experience waning immunity.
Source: Christoph Bock/Max Planck Institute for Informatics

Cancer Prognosis and Survival Predictions Aided by DNA Methylation Patterns

DNA methylation could improve outcomes via more accurate diagnoses of indolent or aggressive tumors requiring different treatment regimens
Qiagen plans to acquire diagnostics developer STAT-Dx for up to $191 million

Qiagen to Acquire Diagnostics Developer STAT-Dx for $147M, Plus Milestones

Later this year, combined company plans to launch QIAstat-Dx, designed for use in oncology and respiratory or gastrointestinal infections
Point mutation, illustration

Treating Ultrarare Diseases, One Patient at a Time

With the aid of the n-lorem Foundation, doctors and patients now have hope of finding treatments to the most rare of genetic diseases.
cancer

Hunting for Hereditary Cancers

A wider reach—in patients and data—promises better outcomes.

Polygenic Risk Scores Taking Hold in the Clinic

Broader, more diverse genomic data sets allow better training of polygenic risk score algorithms, moving them from research models into the clinic.

Clinical OMICs 2021 Pioneers Under 40

This year we highlight a range of leaders in precision medicine ranging from infectious disease experts to CRISPR researchers to company founders.
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