Before patients can be treated with REGEN-COV2 under the EUA, they must weigh at least 40 kilograms (about 88 pounds) and be deemed at high risk for progressing to severe COVID-19 and/or hospitalization. That high-risk category includes adults who are ages 65 or older, or who have chronic medical conditions.
When the researchers suppressed those genes in mouse models of glaucoma they were able to regenerate the damaged axons. The findings could eventually lead to developing therapies for patients of stroke, spinal cord damage, or traumatic brain injuries—avenues that don't currently exists.
According to Myriad, it is the first and only genetic test approved by the FDA as a CDx designed to help identify patients with metastatic pancreatic cancer who have a germline BRCA mutation and are candidates for treatment with Lynparza.
Combining wearable devices, handheld devices and digital apps lets researchers tell the difference between people with early dementia and those without it.
Semen could be considered a liquid biopsy of the organs of male reproductive system—specifically, of the prostate gland. This is convenient. Semen is, potentially,...
Promega’s MSI testing is designed to functionally measure the genomic accumulation of insertion or deletion (INDEL) errors caused by a deficient mismatch-repair system (dMMR) that occurs in certain types of solid tumors.
The study's authors suggested their work could lead to a combination antiviral therapy for COVID-19, which could be especially helpful to unvaccinated people who become infected and to vaccinated people who experience waning immunity.
DNA methylation could improve outcomes via more accurate diagnoses of indolent or aggressive tumors requiring different treatment regimens
The vaccine also showed potential for reducing transmission of the virus, with researchers finding a 67% reduction in positive swabs obtained from volunteers in the U.K. arms of the trials following the first dose.
Later this year, combined company plans to launch QIAstat-Dx, designed for use in oncology and respiratory or gastrointestinal infections
With some positive results in the clinic, there are other encouraging signs the field is maturing and branching into other therapeutic areas such as oncology.
From Mendelian disorders to COVID-19, academic and industrial scientists use these nucleic acids to help diagnose diseases.
In our second installment of women making their mark in the field, Clinical OMICs interviews Bonnie Anderson of Veracyte, Tina Hambuch of Invitae, and Cindy Perettie of Foundation Medicine.
California Medicaid’s pilot program Project Baby Bear delivers better outcomes at lower cost via rapid whole-genome sequencing of critically ill newborns.
A report from the Personalized Medicine Coalition found significant variability in the use of genomic testing for patients not only from state to state, but also within states.